I assume you have power cycled your machine. While that is always the first step of tech support many overlook it.
Zos will respond with a link to something about making sure certain ports are open and that ESOP is on the list of exceptions for your anti virus as their next step. I do not have the link but you can probably google it.
Good luck. Also, I do not expect many responses from Zos themselves until next week since they are pretty much out of the office.