Yes. Especially for those Columbine and Namara's Rot. Never have enough of those, or the guild stores either it seems.
We have been asking this question since early days of Beta. We have Snakeblood which does not really help anyone, as no one needs to make a potion with negative effects. I think you can make a potion that has negative effects, but there are combos that give pretty much anything you need that don't have negative effects.
I have always thought that it should be a passive that gives a better chance to get multiple reagents out of a node. But, now we have that in the Champ System, so maybe they listened to me, lol. I even remember a time when the Increase Farm rate first came out when I was getting 3 to 6 flowers per plant. It only lasted about 3 or 4 days, but it was nice while it was going on. They did extend the increased farm rate to Alchemy Nodes so you can get 4 flowers. Of course the Writs themselves pay in Reagents too.
So, we go back to wanting an Alchemy Hireling. But there may not really be any need for it.
Note, how I farm alchemy is not to go out and farm it specifically, I just pick plants as I go from one place to antother. Usually that means jumping on and off my horse like I have a springboard on my saddle, but it can add up to a surprising amount of reagents in not that long a time frame.