I mention this because I have recently turned off quest markers and found it increased my enjoyment of the game 100%. Previously I found myself running from marker to marker and I felt like I was 'on rails' and was frankly getting quite bored (I know I didn't have to play like this, even with markers turned on - it's merely psychological, but so is enjoyment). Now with markers turned off I don't care about quests so much, I explore more, craft more, talk to all the NPC's in town, try to get equipment from dungeons and mobs or craft it myself, etc. I feel much more closer and involved with the game and am having a lot more fun.
What have you or the devs changed that has made the game more enjoyable for you? This could be a setting, an add-on, a playstyle, a patch, whatever.