It's a bit of an odd one - sometimes pressing E to talk to someone or interact with an object or harvest a node works first time, but other times it doesn't.
I have done thorough troubleshooting on this issue including swapping keyboards and making sure all drivers are up to date, it is not a keyboard/input issue at my end.
What I have noticed is that even when "E" doesn't get the expected response, my character moves towards the object/character slightly and look as though she is about to do something (ie there has been SOME response to my keyboard input) but then fails to carry out the expected action, only a second press of the key will seal the deal. It seems to be more likely to happen when my weapon is drawn, but also happens occasionally when all weapons are sheathed already.
Tbh I often get the same thing in combat, where a key depression does not register the first time, but that's all a bit frantic and I haven't been able to calmly observe it as often as I have when simply harvesting or trying to talk to an NPC.
Edited by Epona222 on May 31, 2014 6:48AM GM - Ghost Sea Trading Co - NA PC
Epona was a Romano-Celtic goddess dating back to around 1800 to 2000 years before computer games were invented.