So, I decided to finally create this topic after long time I wanted to, so people can clearly see the difference in AF and how big this is... which is obviously... huge! So, in one hand, we have, Nvidia app, and AF 16x while
MAX_ANISOTROPY in
Usersettings is the default 0 .... while on the other..... AF in Nvidia is not set while I tested values from 0 to 4 in Usersettings, where obviously none applied and any of them from 1 to 4, lead to longer loading times, indicating that the game was trying to settle this change only to ignore it in the end.
Those pics were taken in 1080p, with Subsampling quality High and all graphics settings tuned for quality in general.... the difference is very clear and all you have to do is to look at the ground, even better if you switch between them few times and see it.
Nvidia is clearly the winner (again)! Not sure if this will work on AMD cards, as I recall their AF is meant for dx9 only, but you could try.

PC specs for the record...... CPU: R7 5800x, GPU: 4060ti, RAM: 2x16 GB, Mainboard: ASUS STRIX B550-A, PSU: Corsair 850W, OS: Win 10