Since MTR came out, while it does improve the frame rate, it also gives some really severe input lag when the GPU is at 100% load. When MTR off, even if the GPU reaches 100% load again, there is no input lag.
I've tried with and without vertical sync and also used Votan's Advanced Settings to turn smoothed frames down to 0 - these make no difference. I am playing in windowed-fullscreen mode, and this is with an AMD Ryzen 1500X @ 3.6GHz and an NVIDIA 1050 Ti 4GB.