I usually take my time with quests and read them before clicking on the conversation options, but since the quest quality dropped and often during mandatory conversations I feel like a child who needs even the most obvious things explained, I started to quickly click through the annoying conversations. This causes that from time to time I oversee a choice and just select the upper one.
For such cases I wish there would be a confirmation requirement for the choice I made, bound to a different button (f.e. "R", its already used in the shop or at benches - E to select and R to confirm). Even if the choices can be often ignored becaue they have no real effect on the game, I would like to keept the illusion that my decision matters and choose the option that I think is right.