Depends on your goals. I think you want to maximize DPS?
Most of your damage comes from magika- or stamina-based abilities?
Well you are a nightblade vampire with daggers you are gonna be a glass cannon. But if most of your skills are magika enchant your weapons with dmg + absorb magika, or you could get Hardening it gives you shield for 5sec. Check this site out if you didn't like what 2 I gave to you, or for further questions of the same topic.
https://docs.google.com/spreadsheets/d/1sWPGogfItnLAfBtNNx_ZRtvglMeUugeSR06V5DQ6FeI/pubhtml