Enjoy! Lag usually causes skills to not fire off.
Though I have had the occasional experience where I have no lag and my skill bar is locked and I can't fire off anything until I "/reloadui"
Lag is a major issue for a lot of players, that Eso seems to ignore.
PvPers are better at their rotations since we have to double-tap each skill in order to get them to fire off =P But yeah...I doubt we will see a meaningful change anytime in the near future.