I started trying this setup yesterday, switching from NM, Agility, Skoria & Leki weapons. This setup has 6 pieces divines, helmet infused and everything is medium legendary.
My Viper/Veledreth/NM setup has only 3 piece divines, 6 medium, 1 lite, mixed purple/legendary. The Veledreth hits much harder than Skoria....when it hits something. My health falls a bit down to 17,800 from 20k . I die quite a bit more. Need to work on that.
My Crit went up to around 70% with Viper. I gotta get more optimal pieces of this setup before making them legendary, but it seems pretty good and hits decently hard. I wouldn't call it the new cheese meta but it seems to have potential.