Let's face it... in your PVE travels you come across A LOT of hamlets, villages and towns. Once you have completed the quests there you move on, and unless its a "hub" town you seldomly, if ever, go back.
What I would like to see is the introduction of some new ambitious Daedric Royalty launching a world attack, with portals/breaches opening up at random times, Daedric creatures pouring out and launching an attack on the nearest village. Players will have to work to ward of these attacks... if a village is "captured" by the Daedric creatures they open up a bigger portal in the town allowing a Daedric Boss, along with bigger and stronger creatures to enter the town and establish a base. A bigger coordinated attack from players will then be required to defeat the Daedric invasion and liberate the village. Possibly having to use Ballistas (in PVE... perish the thought!)

Its just a thought, and yes, inspiration came from Rift. I know the PVE lag issues will need to be sorted to make something like this viable, but many people ask for more solo content, and this is something where you can just group (if you want to) with the players that arrive at the invaded village. It will also encourage players to revisit areas they don't bother with anymore. It would also allow for the introduction of some post- Molag Bal storyline that isn't DLC.
Just a thought.