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So i've testing out the Prox/Soul tether combo with Alchemist Set
Now granted I don't have 501 CP yet (think like 380) ....From what I can tell it'd probably take 4 NBs running that setup to wipe an actual Guild Zerg Ball...You just won't have the damage solo or duo I don't think to do it....I'm averaging around 8k-9k with prox det on these type of groups cause they got enough CP and actually run impen.
I think 4 man though with the right setup and VD on each guy could wipe one of these groups if they're stacked up though...
Against Pugs...I think a Solo NB could wipe a group of randoms fairly easy once VD comes in place and you have like some dude not running Impen dying super quick..It'll basically just take that 1 person dying to setup the others to die.
For the record this is all based off Argonian NB though....Its possible one of the other races with 501 CP might have enough kill power to set it up..But i'm just not certain.