Karma has convinced me to take the squishy things from Alchemy Nodes.
The other day I was in Rivenspire, running to a Wayshrine. I saw a node, opened it up and took the reagent and left the worms behind. As I walked away, I said, don't be that guy, then went back and grabbed the worms.
Along the way to the Wayshrine and this was a short distance, I hit 3 Aspect Rune Nodes in a row, how often does that happen? First two gave me two purple aspects and the next one gave me a Blue aspect stone. So, Karma gave me a gift and I learned my lesson.
Besides, it's not like the Worms and Crawlers don't stack. They can be dumped on the next merchant you come to real easy. And, it's faster to hit R to take all then to select and take one item.