I'm sure that this doesn't bother most people, but it is definitely something that bothers me greatly.
Some side quests leave you with hard decisions, and sometimes I make the wrong one.
For example:
[CLOCKWORK CITY SIDE QUEST SPOILERS AHEAD!] (sorta)
The quest in the Everwound Wellspring was a very tough decision for me. However immediately after I made my choice(to have volunteer sacrifices), I regret it instantly. Sadly, there us no way for me to go back and change my mind.
[END OF SPOILERS]
Ever since then, I've felt really bad about my decision and would love to reverse it. Even if it means repeating the quest with no reward at the end. Anyway, thank you to anyone who listened.