1. Try the Repair Option in the Launcher, it's behind a drop down menu
2. Do any other games (3D type games, not flash games or browser games) work on your machine right now?
3. Have you tried a clean boot http://support.microsoft.com/kb/929135
4. Did you get a challenge and response email from ZOS on first log in?
5. Did you set up an account?
6. Have you contact customer support