I've only been having this problem for the last month, and I'm not exactly sure what's happening but here's a list of things that stop working:
I can't use the ESC button
I can't improve armor
I can't use skill points
I can't enchant armor
There are probably more but those are the ones I know for sure. This doesn't happen when I'm doing any specific action. I've noticed it happen when I'm fighting or idle or crafting.
This is beginning to be a real issue as it's happening more and more frequently to the point that I spend more time quitting and restarting than I do actually playing, which is more than a little frustrating as I pay to play.
Any help would be greatly appreciated.