These are minor, yet significant implement I would like to see as I found them very useful while playing with keyboard+mouse:
1. When looting, I'd like to be able to see if i have the item in my inventory already. On default PC a small icon in the corner of the item would appear with a number to show how many of this you had on you already...the same goes for recipes as in, are they 'Known', or 'Unknown'.
2. I'd like to move items to my junk (i.e. weapons, armor etc.) . This helps a lot by saving time. When looting I can simply drop it in my junk and have all of my junk ready to sell when i go to a merchant which leads me on to my next suggestion...
3. When selling to a merchant I'd really like the option to 'Sell all Junk'. Saves looooads of time and could simply be done with the press of a button.
4. I don't mind not having add ons, especially interface ones, but it would be really helpful if I could have add-ons such as 'Destinations' seeing as I've already played through multiple characters. This doesn't bother me as much as the others but would be nice.
So there you have it. I know these are simply suggestions for 'ease of access' but with them my experience would be MUCH better - it just bothers me they're not there because they're so useful, especially the first 3

I'm sure other people have more suggestions so let me know if you agree with mine and add your own below...let's get zos to see!
There's a difference between knowing the path and walking the path.